Michael E. Wall

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Biographical info:

  • Scientist at Los Alamos National Laboratory in the Computer, Computational, and Statistical Sciences Division.
  • Ph.D. Physics, Princeton University; B.S. Physics, UC San Diego
  • My past work has used molecular simulations and X-ray diffraction data to provide insights into protein dynamics and protein function.
  • I am currently focused on diffuse X-ray scattering from protein crystals,integrating quantum electronic structure calculations into X-ray crystallography, and high-performance computing.

    Selected publications:

    A. H. Van Benschoten, L. Liu, A. Gonzalez, A. S. Brewster, N. K. Sauter, J. S. Fraser, M. E. Wall. 2016. Measuring and modeling diffuse scattering in protein X-ray crystallography. Proc Natl Acad Sci USA 113:4069. (pdf; URL)

    M. E. Wall, A. H. Van Benschoten, N. K. Sauter, P. D. Adams, J. S. Fraser, T. C. Terwilliger. 2014. Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering. Proc Natl Acad Sci USA 50:17887-17892. (pdf; PubMed)

    M. E. Wall, Ed., Quantitative Biology: From Molecular to Cellular Systems. Boca Raton: Chapman & Hall, 2012. (URL)

    D. Ming, M. E. Wall. 2005. Allostery in a coarse-grained model of protein dynamics. Phys Rev Lett 95:198301. (PubMed; URL). Preprint (pdf). arXiv (q-bio.BM/0506031).

    M.E. Wall, S.H. Francis, J.D. Corbin, K. Grimes, R. Richie-Jannetta, J. Kotera, B.A. Macdonald, R.R. Gibson, J. Trewhella. 2003. Mechanisms associated with cGMP binding and activation of cGMP-dependent protein kinase. Proc Natl Acad Sci USA 100:2380-2385. (PubMed)

    M.E. Wall, S.E. Ealick and S.M. Gruner. 1997. Three-dimensional diffuse X-ray scattering from crystals of Staphylococcal nuclease. Proc Natl Acad Sci USA 94:6180-6184. (PubMed)

    Michael Wall / mewall@lanl.gov
    Los Alamos National Laboratory, CCS-3 MS B256, Los Alamos NM 87545
    tel: 505.665.4209 / fax: 505.667.1126

    Last modified Friday, 24-Jun-2016 09:11:37 MDT