Publication

Journal articles

1. Shudo E, Ribeiro RM, Talal AH, Perelson AS. A Hepatitis C Viral Kinetic Model that Allows for Time-Varying Drug Effectiveness. Antivir Therapy in press.

2. Klatt N, Shudo E, Ortiz A, Engram J, Paiardini M, Lawson B, Miller M, Else J, Schmitz J, Ribeiro RM, Perelson AS. Depletion of CD8+ T Cells Does Not Affect the Lifespan of Productively Infected Cells During Pathogenic SIVmac239 Infection of Rhesus Macaques. Nature Medicine Under review.

3. Dahari H, Shudo E, Ribeiro RM, Perelson AS. Modeling Complex Decay Profiles of Hepatitis B Virus during Antiviral Therapy. Hepatology in press.

4. Thompson A, Shudo E, Rubiero R, Visvanathan K, Desmond P, Lau G, Perelson A, Locarnini S. New insights into HBV pathogenesis from kinetic analysis of HBeAg titre decay during potent antiviral therapy. Hepatology AASLD 2008 Poster, accepted.

5. Dahari H, Shudo E, Cotler SJ, Layden TJ, Perelson AS. Modeling HCV kinetics: Finding a drug effectiveness threshold beyond which the final slope of viral decay represents the infected cells loss rate. Antiviral Therapy under review.

6. Shudo E, Ribeiro RM, Perelson AS. Modelling hepatitis C virus kinetics during treatment with pegylated interferon alpha-2b: errors in the estimation of viral kinetic parameters. Journal of Viral Hepatitis 2008 May;15(5):357-362.

7. Shudo E, Ribeiro RM, Perelson AS. Modelling the kinetics of hepatitis C virus RNA decline over 4 weeks of treatment with pegylated interferon alpha-2b. Journal of Viral Hepatitis 2008 May;15(5):379-382.

8. Shudo E, Ribeiro RM, Perelson AS. Hepatitis C Virus Kinetics During Treatment With Pegylated Interferon a-2b. Hepatology International 2007;1(1):36.

9. Lau GK, Cooksley H, Ribeiro RM, Powers KA, Shudo E, Bowden S, Hui CK, Anderson J, Sorbel J, Mondou E, Rousseau F, Lewin S, Perelson AS, Locornini S, Naoumov NV. Impact of early viral kinetics on T-cell reactivity during antiviral therapy in chronic hepatitis B. Antivir Therapy 2007;12(5):705-718.

10. Shudo E, Yang J, Yoshimura A, Iwasa Y. Robustness of the signal transduction system of the mammalian JAK/STAT pathway and dimerization steps. Journal of Theoretical Biology 2007 May 7;246(1):1-9.

11. Shudo E, Iwasa, Y. . Dynamic optimization of host defense, immune memory, and post-infection pathogen levels in mammals. International Symposium on Dynamical Systems Theory and Its Applications to Biology and Environmental Sciences 2004;1:145.

12. Shudo E, Iwasa Y. Dynamic optimization of host defense, immune memory, and post-infection pathogen levels in mammals. Journal of Theoretical Biology 2004 May 7;228(1):17-29.

13. Shudo E, Haccou P, Iwasa Y. Optimal choice between feedforward and feedback control in gene expression to cope with unpredictable danger. Journal of Theoretical Biology 2003 Jul 21;223(2):149-160.

14. Shudo E, Iwasa Y. Optimal defense strategy: storage vs. new production. Journal of Theoretical Biology 2002 Dec 7;219(3):309-323.

15. Shudo E, Iwasa Y. Inducible defense against pathogens and parasites: optimal choice among multiple options. Journal of Theoretical Biology 2001 Mar 21;209(2):233-247.

Book chapter

16. Dahari H, Shudo E, Ribeiro RM, Perelson AS. Mathematical modeling of HCV infection and treatment. . In: Tangli H, editor. Hepatitis C protocols 2nd Ed. ed. NJ: Humana Press; in press.