Michael E. Wall


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Biographical info:

  • Scientist at Los Alamos National Laboratory in the Computer, Computational, and Statistical Sciences Division.
  • Ph.D. Physics, Princeton University; B.S. Physics, UC San Diego
  • My past work has used molecular simulations and X-ray diffraction data to provide insights into protein dynamics and protein function.
  • I am currently focused on diffuse X-ray scattering from protein crystals,integrating quantum electronic structure calculations into X-ray crystallography, and high-performance computing.

    Selected publications:

    A. H. Van Benschoten, L. Liu, A. Gonzalez, A. S. Brewster, N. K. Sauter, J. S. Fraser, M. E. Wall. 2016. Measuring and modeling diffuse scattering in protein X-ray crystallography. Proc Natl Acad Sci USA (in press). (bioRxiv)

    M. E. Wall, A. H. Van Benschoten, N. K. Sauter, P. D. Adams, J. S. Fraser, T. C. Terwilliger. 2014. Conformational dynamics of a crystalline protein from microsecond-scale molecular dynamics simulations and diffuse X-ray scattering. Proc Natl Acad Sci USA 50:17887-17892. (pdf; PubMed)

    M. E. Wall, Ed., Quantitative Biology: From Molecular to Cellular Systems. Boca Raton: Chapman & Hall, 2012. (URL)

    D. Ming, M. E. Wall. 2005. Allostery in a coarse-grained model of protein dynamics. Phys Rev Lett 95:198301. (PubMed; URL). Preprint (pdf). arXiv (q-bio.BM/0506031).

    M.E. Wall, S.H. Francis, J.D. Corbin, K. Grimes, R. Richie-Jannetta, J. Kotera, B.A. Macdonald, R.R. Gibson, J. Trewhella. 2003. Mechanisms associated with cGMP binding and activation of cGMP-dependent protein kinase. Proc Natl Acad Sci USA 100:2380-2385. (PubMed)

    M.E. Wall, S.E. Ealick and S.M. Gruner. 1997. Three-dimensional diffuse X-ray scattering from crystals of Staphylococcal nuclease. Proc Natl Acad Sci USA 94:6180-6184. (PubMed)


    Michael Wall / mewall@lanl.gov
    Los Alamos National Laboratory, CCS-3 MS B256, Los Alamos NM 87545
    tel: 505.665.4209 / fax: 505.667.1126

    Last modified Tuesday, 01-Mar-2016 14:31:29 MST